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- Molecular Formula: C8H8 Br Cl
- Molecular Weight: 219.509
- Vapor Pressure: 0.0623mmHg at 25°C
- Refractive Index: n20/D 1.5707(lit.)
- Boiling Point: 110-112 °C10 mm Hg
- Flash Point: >230 °F
- PSA: 0.00000
- Density: 1.4569 g/mL at 25 °C(lit.)
- LogP: 3.27740
2-CHLOROPHENETHYL BROMIDE(Cas 16793-91-2) Usage
|
General Description |
2-Chlorophenethyl bromide is an organic compound that consists of a benzene ring with a chlorine atom and a bromine atom attached to it. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is also known for its application as a reagent in organic chemistry, particularly in the preparation of various types of compounds including ethers and esters. It is a colorless to pale yellow liquid that is volatile and has a strong, unpleasant odor. 2-Chlorophenethyl bromide is also known by its alternative name, 2-bromoethyl benzene, and has the chemical formula C8H8BrCl. It is important to handle this compound with caution as it is considered to be toxic and may cause irritation to the skin, eyes, and respiratory system. |
InChI:InChI=1/C8H8BrCl/c9-6-5-7-3-1-2-4-8(7)10/h1-4H,5-6H2
16793-91-2 Relevant articles
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Barnes,Konort
, p. 303 (1953)
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Para-Selective C-H Borylation of Common Arene Building Blocks Enabled by Ion-Pairing with a Bulky Countercation
Mihai, Madalina T.,Williams, Benjamin D.,Phipps, Robert J.
supporting information, p. 15477 - 15482 (2019/10/11)
The selective functionalization of C-H b...
Preparation method for hemihydrate lorcaserin hydrochloride
-
Paragraph 0106; 0107, (2017/08/28)
The invention discloses a preparation me...
Scalable anti-Markovnikov hydrobromination of aliphatic and aromatic olefins
Galli, Marzia,Fletcher, Catherine J.,Del Pozo, Marc,Goldup, Stephen M.
supporting information, p. 5622 - 5626 (2016/07/06)
To improve access to a key synthetic int...
Construction of chiral 2-substituted octahydroindoles from cyclic ketones and nitroolefins bearing only one α-substituent
Han, Yong,Zheng, Bo,Peng, Yungui
supporting information, p. 1136 - 1142 (2015/04/22)
A dual catalytic system has been develop...
16793-91-2 Process route
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-
19819-95-5
2-(2-chlorophenyl)-1-ethanol
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-
16793-91-2
1-(2-bromoethyl)-2-chlorobenzene
| Conditions | Yield |
|---|---|
|
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
at 0 - 20 ℃;
|
84%
|
|
With
phosphorus tribromide;
In
benzene;
1.) 0 deg C, 1 h, 2.) reflux, 3 h;
|
78%
|
|
With
phosphorus tribromide;
|
|
|
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
|
|
|
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
at 0 - 25 ℃;
|
|
|
With
phosphorus tribromide;
at 0 - 80 ℃;
for 2.16667h;
|
22.4 g
|
-
-
2039-87-4,107830-52-4,26125-41-7
2-chlorostyrene
-
-
16793-91-2
1-(2-bromoethyl)-2-chlorobenzene
| Conditions | Yield |
|---|---|
|
With
hydrogen bromide; acetic acid;
In
hexane;
at 0 ℃;
for 2h;
|
99%
|
16793-91-2 Upstream products
-
19819-95-5
2-(2-chlorophenyl)-1-ethanol
-
2444-36-2
2'-chloro-benzeneacetic acid
-
2039-87-4
2-chlorostyrene
16793-91-2 Downstream products
-
96626-63-0
1-[2-(2-Chloro-phenyl)-ethyl]-4-(3-methoxy-phenyl)-3,3-dimethyl-4-phenyl-piperidine
-
96626-49-2
1-[2-(2-Chloro-phenyl)-ethyl]-4-(3-methoxy-phenyl)-3,3,4-trimethyl-piperidine
-
131911-22-3
S-(2-(2-chlorophenyl)ethyl)isothiourea hydrobromide
-
1643-28-3
3-(2-chlorophenyl)propanoic acid