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What is the L-655,708 ?
L-655,708 is powder, while it's Molecular Formula is C18H19N3O4. L-655,708 has been used as an α5 GABAA receptor inverse agonist to inhibit the discriminative stimulus of propofol in a dose-dependent manner.
What is the CAS number for L-655,708 ?
The CAS number of L-655,708 is 130477-52-0.
More information of L-655,708 130477-52-0 are:
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Synonyms |
(S)-9-Methoxy-7-oxo-3β,4,5,6-tetrahydro-7H-2,6α,11b-triaza-benzo[g]cyclopenta[e]azulene-3-carboxylic acid ethyl ester; |
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CAS?Number |
130477-52-0 |
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Molecular Formula |
C18H19N3O4 |
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Molecular Weight |
341.367 |
|
Density |
1.42 g/cm3 |
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Melting Point |
175-176 °C |
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Boiling Point |
584.4 °C at 760 mmHg |
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Flash Point |
307.2 °C |
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PSA |
73.66000 |
|
LogP |
2.28620 |
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Pka |
1.49±0.20(Predicted) |
What is L-655,708 (130477-52-0) used for?
L-655,708 is a pharmaceutical compound that functions as an α5 GABAA receptor inverse agonist. It is designed to modulate the activity of the α5 subunit of the GABAA receptor, which plays a crucial role in various neurological and cognitive processes.
InChI:InChI=1/C18H19N3O4/c1-3-25-18(23)15-16-14-5-4-8-20(14)17(22)12-9-11(24-2)6-7-13(12)21(16)10-19-15/h6-7,9-10,14H,3-5,8H2,1-2H3/t14-/m0/s1
Articles related to L-655,708:
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Article |
Source |
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Optimization of substituted imidazobenzodiazepines as novel asthma treatments |
Jahan, Rajwana,Stephen, Michael Rajesh,Forkuo, Gloria S.,Kodali, Revathi,Guthrie, Margaret L.,Nieman, Amanda N.,Yuan, Nina Y.,Zahn, Nicolas M.,Poe, Michael M.,Li, Guanguan,Yu, Olivia B.,Yocum, Gene T.,Emala, Charles W.,Stafford, Douglas C.,Cook, James M.,Arnold, Leggy A. , p. 550 - 560 (2017) |
How to get the best price on L-655,708?
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