Quality Factory Supply 99% Pure MG-132 133407-82-6 with Efficient Delivery

Q: What is the MG-132?

MG-132 is solid film, while it's Molecular Formula is C 26 H 41 N 3 O 5 . solid film MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.

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Quality Factory Supply 99% Pure MG-132 133407-82-6 with Efficient Delivery We supply high quality MG-132 (CAS 133407-82-6), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the MG-132 ?

MG-132 is solid film, while it's Molecular Formula is C₂₆H₄₁N₃O₅. MG 132 is a potent, membrane-permeable proteasome inhibitor. It induces neurite outgrowth in PC12 cells. Neuroprotective product.

What is the CAS number for MG-132 ?

The CAS number of MG-132 is 133407-82-6.

More information of MG-132 133407-82-6 are:

Synonyms	L-Leucinamide,N-[(phenylmethoxy)carbonyl]-L-leucyl-N-(1-formyl-3-methylbutyl)-, (S)-;MG 132;
CAS?Number	133407-82-6
Molecular Formula	C₂₆H₄₁N₃O₅
Molecular Weight	475.629
Density	1.073 g/cm³
Melting Point	80-84℃ (DEC.)
Boiling Point	682 °C at 760 mmHg
Flash Point	366.3 °C
HS CODE	29242990
PSA	113.60000
LogP	4.76090
Pka	11.14±0.46(Predicted)

What is MG-132 (133407-82-6) used for?

MG-132 (133407-82-6) is a specific inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50=100 nM with Z-LLL-AMC as substrate).1 Also inhibits calpain (IC50=1.25 μM).1 Suppresses gastric cancer cell proliferation and induces macro-autophagy.2 Activates stress kinases and induces Hsp72.3 Induces neurite outgrowth.1 MG-132 blocks NFκB activation by blocking IκB proteolysis (IC50=3 μM).4 Cell permeable.

InChI:InChI=1/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1

Articles related to MG-132:

Article

Source

Application of proteasome inhibitor in inhibition of novel coronavirus

Paragraph 0130; 0146-0148, (2021/06/22)

Systematic comparison of peptidic proteasome inhibitors highlights the α-ketoamide electrophile as an auspicious reversible lead motif

Stein, Martin L.,Cui, Haissi,Beck, Philipp,Dubiella, Christian,Voss, Constantin,Krueger, Achim,Schmidt, Boris,Groll, Michael

supporting information, p. 1679 - 1683 (2014/03/21)

How to get the best price on MG-132?

Hangzhou Now Chemicals Co; Limited. is a quality supplier and manufacturer of MG-132 . You can buy high quality, low price MG-132 133407-82-6 here. Contact us.