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Chinese Manufacturer supply 2-AMINO-6-METHYLHEPTANE 543-82-8 in stock with high standard
- Molecular Formula:C8H19N
- Molecular Weight:129.246
- Appearance/Colour:clear colorless to light yellow liquid
- Vapor Pressure:3.09mmHg at 25°C
- Melting Point:25°C
- Refractive Index:n20/D 1.422(lit.)
- Boiling Point:154.999 °C at 760 mmHg
- PKA:pKa 10.28 ± 0.1(H2O,t =25±0.2,I<0.001) (Uncertain)
- Flash Point:48.889 °C
- PSA：26.02000
- Density:0.783 g/cm3
- LogP:2.86020
2-AMINO-6-METHYLHEPTANE(Cas 543-82-8) Usage
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Preparation |
1,5-Dimethylhexylamine was synthesized from 6-methyl-2-heptanone ([928-68-7]) by amination and catalytic hydrogenation. |
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Application |
1,5-Dimethylhexylamine can be used as a local anesthetic and vasoconstrictor, and it is mainly used as an intermediate in the production of gastrointestinal antispasmodic drug octamylamine. |
InChI:InChI=1/C8H19N/c1-7(2)5-4-6-8(3)9/h7-8H,4-6,9H2,1-3H3/p+1/t8-/m0/s1
543-82-8 Relevant articles
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Rohrmann,Shonle
, p. 1516,1518 (1944)
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Reusable Nickel Nanoparticles-Catalyzed Reductive Amination for Selective Synthesis of Primary Amines
Murugesan, Kathiravan,Beller, Matthias,Jagadeesh, Rajenahally V.
supporting information, p. 5064 - 5068 (2019/03/19)
The preparation of nickel nanoparticles ...
En route to (S)-selective chemoenzymatic dynamic kinetic resolution of aliphatic amines. One-pot KR/racemization/KR sequence leading to (S)-amides
El Blidi, Lahssen,Nechab, Malek,Vanthuyne, Nicolas,Gastaldi, Stephane,Bertrand, Michele P.,Gil, Gerard
supporting information; experimental part, p. 2901 - 2903 (2009/09/05)
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543-82-8 Process route
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70419-11-3,70419-10-2
(R)-6-methylheptan-2-amine
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543-82-8,70419-10-2
1,5-dimethylhexylamine
| Conditions | Yield |
|---|---|
|
With
2,2,2-trifluoroethanethiol;
In
tetrahydrofuran; 3-methylpentan-3-ol;
at 22 - 24 ℃;
for 2h;
Photolysis;
|
-
-
543-82-8,70419-10-2
1,5-dimethylhexylamine
| Conditions | Yield |
|---|---|
|
With
nickel;
Hydrogenation;
|
|
|
With
ethanol; sodium;
|
543-82-8 Upstream products
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540-69-2
ammonium formate
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928-68-7
6-methylheptan-2-one
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70419-11-3
(R)-6-methylheptan-2-amine
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110-93-0
6-Methyl-hept-5-en-2-on
543-82-8 Downstream products
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502-59-0
octamylamine
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30121-80-3
4-{[(E)-1,5-Dimethyl-hexylimino]-methyl}-2-ethoxy-phenol
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15332-58-8
Bis-(2-chloro-ethyl)-(4-{[(E)-1,5-dimethyl-hexylimino]-methyl}-3-methyl-phenyl)-amine
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30121-85-8
(1,5-Dimethyl-hexyl)-[2-[1-phenyl-meth-(E)-ylidene]-oct-(E)-ylidene]-amine
